Restylane® Defyne

As we age, our skin loses elasticity and the lines that run from the sides of the nose toward the corners of the mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) become more pronounced. Restylane Defyne is crafted with XpresHAn Technology™ to correct these deepened lines.

The unique cross-linking of the gel in Restylane Defyne is also designed to help support your facial expressions—for natural-looking results that help maintain your natural movement.

Restylane® Defyne and Restylane® Refyne are the only fillers on the market that have been shown in a clinical study to help maintain movement and expressions.

Restylane® Defyne is injected into the mid to deep facial tissue to correct moderate to severe facial wrinkles and folds, such as nasolabial folds.

Some people may experience the treatment as a mild discomfort. Many Restylane products contain an integrated local anesthetic, lidocaine, to provide you with a more comfortable treatment experience. You and your healthcare professional may decide whether additional pain relief is needed.

Your doctor will cleanse and prepare the area(s) to be treated. The clear gel in the Restylane family of products is injected into the treatment area(s) using an ultra-fine needle to create the desired aesthetic effect. After injection, he/she may gently massage the treated area.

A treatment with Restylane® Defyne doesn’t usually take long. A touch-up treatment is sometimes performed after the initial treatment to optimize your results. Talk to your healthcare professional to learn more about the treatment procedure.

After your initial treatment, you can refresh your look with a follow-up treatment, as determined by your healthcare professional. Additional treatments can help refresh the immediate results of your initial treatment.

Restylane® is the world’s best-selling dermal filler. It is well tolerated, nonsurgical and long lasting (usually around six months).

In a clinical study, subjects were evaluated based on perception of the naturalness of facial expressions in motion after 1 month of Restylane® Defyne and Restylane® Refyne optimal treatment. As a result, 97% were satisfied with their treatment results and would do the treatment again, and 95% would recommend the products to a friend.